Reactive oxygen species (ROS)-responsive prodrug nanoplatforms may not work efficiently due to insufficient ROS concentrations, so therapeutic polymersomes of a metallisable triamine-centered iminoboronate-functionalized amphiphilic starlike prodrug (N3-(OEG-IBCAPE)4) are prepared to show a Cu(II)-mediated Fenton reaction-enhanced ROS response.

https://pubs.rsc.org/en/content/articlelanding/2020/CC/D0CC03607B#!divAbstract