首页
最新动态 交流合作 科研项目 论文著作 精彩瞬间 招生招聘
  • Lethal puncturing of planktonic Gram-positive and Gram-negative bacteria by magnetically-rotated silica hexapods
  • 来源:张泽新教授个人网站 2024-08-26
  • Planktonic bacterial presence in many industrial and environmental applications and personal health-care products is generally countered using antimicrobials. However, antimicrobial chemicals present an environmental threat, while emerging resistance reduces their efficacy. Suspended bacteria have no defense against mechanical attack. Therefore, we synthesized silica hexapods on an alpha-Fe(2)O(3) core that can be magnetically-rotated to inflict lethal cell-wall-damage to planktonic Gram-negative and Gram-positive bacteria. Hexapods possessed 600 nm long nano-spikes, composed of SiO(2), as shown by FTIR and XPS. Fluorescence staining revealed cell wall damage caused by rotating hexapods. This damage was accompanied by DNA/protein release and bacterial death that increased with increasing rotational frequency up to 500 rpm. Lethal puncturing was more extensive on Gram-negative bacteria than on Gram-positive bacteria, which have a thicker peptidoglycan layer with a higher Young''s modulus. Simulations confirmed that cell-wall-puncturing occurs at lower nano-spike penetration levels in the cell walls of Gram-negative bacteria. This approach offers a new way to kill bacteria in suspension, not based on antimicrobial chemicals.

  • [来源:中国聚合物网]
  • 了解更多请进入: 张泽新教授个人网站
相关新闻
  • · Comparative study of the dynamics of colloidal glass and gel
  • · 2D Colloidal Crystals with Anisotropic Impurities
  • · Reconfiguring Self-Assembly of Photoresponsive Hybrid Colloids
  • · Motor and Rotor in One: Light-Active ZnO/Au Twinned Rods of Tunable Motion Modes

关于我们  |  联系我们  

网站:中国聚合物网

polymer.cn Copyright ©2017