内容简介：
【简介】
Research Areas:
In the Penn Chemistry Department a broad range of biological problems are being attacked, from the structure of proteins and nucleic acids, to enzyme mechanisms, to neurochemistry. Techniques in use cover all of modern chemistry: NMR spectroscopy, X-ray and neutron diffraction, laser and synchrotron radiation, as well as recombinant and synthetic DNA approaches.
The inorganic chemistry program at Penn is unusually diverse and interdisciplinary in nature, encompassing synthetic, spectroscopic, structural, mechanistic, and theoretical research programs involving new molecular, polymeric, and solid-state compounds and materials. A major emphasis in many of the research programs is the design and synthesis of new molecules and materials having specific chemical or physical properties. Some specific areas of current interest include: metallo-radicals, electron and energy transfer reactions, metallo-enzymes and the de novo synthesis of artificial metalloproteins, main group chemistry, transition-metal catalyzed reactions of organic and inorganic compounds, solid-state chemistry, new conducting polymers and liquid crystals, inorganic polymers, ceramic processing, and molecules and materials with novel optical properties.
Organic Chemistry at Penn encompasses the study of organic synthesis, conducting polymers, bioorganic chemistry, organometallic chemistry, photochemistry, and physical organic chemistry. Programs are available in new synthetic methodology, synthesis of novel polymers and liquid crystals, total synthesis of natural products with anticancer, antibiotic, antiallergic, and antithrombotic action, the design and synthesis of biologically interesting compounds, mechanistic organic chemistry, and the synthesis of theoretically interesting molecules. Current projects cover a wide spectrum of topics ranging from synthesis of macrolides, polyethers, cyclopentanoids, alkaloids, marine natural products, pheromones, cyclic peptides, anthracyclines, sphingolipids, nucleotides, and carbohydrates, to organometallic and organofluorine chemistry and NMR studies of organic and bioorganic molecules. Molecular modeling is an increasingly important part of organic chemistry. Current applications at Penn ran ge from molecular mechanics to high-level ab initio molecular orbital calculations.
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