内容简介:
【简介】 Department of Pharmaceutical Chemistry can select a molecule as the target and figure out how to affect that molecule in a way that will stop the pathologic biological process with minimal effect on healthy biological processes. Typically, they try to design a drug molecule which will bind selectively to the target molecule but not to others. Knowing the three-dimensional structure of the target molecule is a most useful starting point for drug design. Faculty research in the department spans the range from discovering the molecular details of the biological processes to structure determination and subsequently to drug design, including protein engineering. Much of this is aided by computer-guided approaches. A significant faculty effort is put into developing the methodology for drug development which is used worldwide in rearch institutes and in biotechnology and pharmaceutical companies.