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CATIONIC COMB-TYPE COPOLYMER TO MANIPULATE DNA AND PEPTIDE FOLDING
DNA is a highly charged polyanion so that its hybridization and folding are largely affected by ionic interactions of phosphate groups in DNA backbones.
http://www.polymer.cn/research/dis_info11907

DNA 折纸术纳米反应器
生物体中，功能性的生物大分子被精确定位集成在限域空间内并进行高效的生化反应。受此启发，我们提出通过 DNA 折纸术技术，构建具有纳米尺度可控定位能力的纳米限域空间（纳米反应器），并进而实现对生化反应的精确调控。首先，我们深入研究了 DNA 折纸术结构的组装过程，发现仅用 10-20 分钟即可组装出分子量高达 4.8M 的长方形 DNA 折纸术结构（与核糖体相近），以及更为复杂的由这些长方形作为单体形成的 DNA 纳米带和纳米...
http://www.polymer.cn/research/sy_info16828

Kinetics of DNA assembly monitored by time-resolved laser light scattering
DNA nanotechnology with DNA tiles as the basic building blocks has been an attractive research topic and a most promising self-assembly technology since 1980s.
http://www.polymer.cn/research/dis_info16839

Plasmid-templated shape control of condensed DNA–block copolymer nanoparticles
A central objective in gene delivery is the ability to direct the transport properties, cellular uptake and delivery efficiency of DNA-containing nanoparticles. Recently, nanoparticle shape has been identified as an important factor determi...
http://www.polymer.cn/research/dis_info16812

Control the Molecular Interactions with DNA Nanomachine
关键字：DNA, self-assembly, nanomachine, polyvalency, dynamics
Polyvalent interactions are characterized by the simultaneous binding of multiple ligands on one biological entity to multiple receptors on another. Comparing to corresponding monovalent interactions, polyvalent interactions often have cooperative ef...
http://www.polymer.cn/research/dis_info16327

High Temperature, Organic Ferromagnetic Compositions A Lesson Learned From DNA Science
Materials Science of DNA is in its infant stage although DNA has been enjoying for the past half century the pivotal importance in bioscience and biotechnology.
http://www.polymer.cn/research/dis_info16017

DNA智能材料与纳米器件
生物大分子在受到外界刺激时能够产的二级结构变化是命活动赖以存基础。利用生命系统中存在的生物大分子二级结构应激改变构建可以活动纳米器件是生物纳米技术研究的追求目标之一，对我们了解命奥秘、构建生物传感器以及仿生纳米器件的研究都有着重要意义。
http://www.polymer.cn/research/dis_info14868

DNA 自组装纳米技术
纽约大学Seeman 教授开创的DNA 自组装纳米技术是纳米科学领域最受关注的平台工程，Watson－Crick 的碱基配对规则和DNA 瓦的刚性使得程序化地自组装DNA 晶体和纳米器件成为可能，例如用DNA可以构成立方体、四面体、八面体、二维和三维的晶体、以及各种纳米机器人等，在过去的十多年里，研究人员还尝试了使用多种DNA 轭合物的构筑块，如DNA－纳米粒、DNA－蛋白质、和DNA－RNA 等，这些在纳米量级...
http://www.polymer.cn/research/dis_info13250

HOW CHAINS FREE IN MIXTURE OF PEI AND DNA PROMOTE GENE TRANSFECTION
Our revisit of the complexation between anionic DNA and cationic polyethylenimine (PEI) in both water and phosphate buffered saline (PBS) by using a combination of laser light scattering (LLS) and gel electrophoresis confirms that ...
http://www.polymer.cn/research/dis_info13127

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