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【Nanoscale-2018年冬季】Design of smart targeted and responsive drug delivery systems with enhanced antibacterial properties
The use of antibiotics has been an epoch-making invention in the past few decades for the treatment of infectious diseases. However, intravenous injection of antibiotics lacking responsiveness and targeting properties led to the low drug utilization and high cytotoxicity. More importantly, it also caused the development and spread of drug-resistant bacteria due to the repeated medicati...
http://www.polymer.cnt//ss/wangbailiang/publicationsshow_13390.html |
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【Carbohydrate Polymers-2018年冬季】Synthesis of chitosan-based micelles for pH responsive drug release and antibacterial application
The over- and inefficient release of antibiotics from common delivery systems causes the development of drug-resistant bacteria. In the present work, methoxy poly(ethylene glycol)-poly(ε-caprolactone)-chitosan/montmorillonite (MPC/MMT) hybrid multilayer films were constructed for bacterial infections and pH-dependent release of the hydrophobic drug triclosan (TCA). The thickness of the (MP...
http://www.polymer.cnt//ss/wangbailiang/publicationsshow_13315.html |
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【Journal of Materials Chemistry B-2018年春季】Recent developments in smart antibacterial surfaces to inhibit biofilm formation and bacterial infections
Since their development over 70 years, antibiotics are still the most effective strategy to treat bacterial biofilms and infections. However, the overuse of antibiotics in human healthcare and industrial applications has resulted in the development of serious antibiotic-resistant bacteria. Therefore, alternative ways to prevent bacteria attachment and biofilm formation are urgentl...
http://www.polymer.cnt//ss/wangbailiang/publicationsshow_13313.html |
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【Chemical Engineering Journal-2018年秋季】Construction of nanomaterials with targeting phototherapy properties to inhibit resistant bacteria and biofilm infections
The spread of resistant bacteria and the development bacterial biofilm have been two major challenges in the application of biomaterials, causing device failure as well as tissue infections. The overuse of antibiotics has become a common cause of the emergence of multiple antibiotics-resistant bacteria. Besides, biofilm infections are notoriously difficult to treat, as the biofilm...
http://www.polymer.cnt//ss/wangbailiang/publicationsshow_13311.html |
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【Journal of Materials Chemistry B-2015年春季】Hydrated polysaccharide multilayer as an intraocular lens surface coating for biocompatibility improvements
Posterior capsule opacification (PCO) is a significant complication of intraocular lens (IOL) implantation in cataract surgery, in which the adhesion and proliferation of lens epithelial cells (LECs) on the IOL surface play important roles. In the present study, a highly swollen hyaluronic acid (HA)/chitosan (CHI) polyelectrolyte multilayer was fabricated on the IOL surface via th...
http://www.polymer.cnt//ss/wangbailiang/publicationsshow_13308.html |
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【Nanoscale-2016年冬季】Targeted delivery of doxorubicin to tumour tissues by a novel legumain sensitive polygonal nanogel
Targeted delivery of cytotoxic drugs to tumour tissue has great importance for successful chemotherapy. Legumain is an asparaginyl endopeptidase that is highly up-regulated in a number of solid tumours. The aim of this work was to prepare a novel hyaluronic acid (HA) based legumain sensitive nanogel for the delivery of doxorubicin with a high targeting efficiency both in vitro and in vivo. The l...
http://www.polymer.cnt//ss/wangbailiang/publicationsshow_13306.html |
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【JMCB-2017年秋季】Bacterial infection microenvironment-responsive enzymatically degradable multilayer films for multifunctional antibacterial properties
The adhesion of bacteria is one of the most important stages in biofilm formation and bacterial infection.
Once bacteria have adhered to a biomaterial surface, it is hard to eliminate them, and bacterial growth and
infection are inevitable. In the current study, we have designed and constructed enzymatically degradable
(hyaluronic acid/chitosan)n–(hyaluronic acid/polylysine)n ((HA/CHI)...
http://www.polymer.cnt//ss/wangbailiang/publicationsshow_12360.html |
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2014年全国高分子材料科学与工程研讨会
http://www.polymer.cn/research/dis_list/82 |
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2013年全国高分子学术论文报告会（2013.10.12~16，上海）
http://www.polymer.cn/research/dis_list/80 |
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2011年全国高分子学术论文报告会（2011.9.24~28，大连）
http://www.polymer.cn/research/dis_list/60 |
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