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Magnetic-DNA vector constructed from PDMAEMA polycation and PEGylated brush-type polyanion with crosslinkable shell
Gene therapy has been known as a promising treatment for numerous hard curable diseases, and its safety and efficiency play the most challenging role.
http://www.polymer.cn/research/dis_info16694 |
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ATP诱导的DNA突环结构的打开及其对DNA链替换反应的调控
关键字:DNA突环结构,ATP适配体,分子开关,DNA链替换反应 DNA分子具有精确的碱基识别能力和序列可编程性,作为一种理想组装材料,近年来已被用于设计构建纳米尺度的分子器件,这些运转和调控通常是经一系列精确有序的DNA链替换反应来实现的。
http://www.polymer.cn/research/dis_info15411 |
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Dominant Process Which Influence Optical DNA Sequence Detection using Conjugated Polymers
关键字:DNA Sequence Detection A fluorescence method for detecting a target nucleic acid sequence, in a strategy employing acombination of a labeled peptide nucleic acid (PNA-C*) probes and conjugated polymer (CCP)/surfactant system, in a simple, rapid, and sensitiv...
http://www.polymer.cn/research/dis_info8922 |
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Novel quasi-interpenetrating network/gold nanoparticles composite matrices for DNA sequencing performances by capillary electrophoresis
Sieving matrices are very important because they determine migration behavior and resolution of DNA during separation and sequencing analysis of DNA by capillary Electrophoresis (CE).
http://www.polymer.cn/research/dis_info8808 |
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Amphiphilic fluorescent tryptophan-containing copolymer: synthesis, characterization and interaction with DNA
关键字:amphiphilic copolymer, DNA, fluorescence Much attention has been paid to amphiphilic copolymers containing chromophores because of their unique photophysical and photochmical behavior in aqueous solution. Yokoyama et al. reported the use of amphiphilic copolymer in gene delivery&n...
http://www.polymer.cn/research/dis_info3289 |
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DNA AS A FUNCTIONAL MATERIAL —REMOVAL OF DIOXIN DERIVATIVES BY SALMON MILT DNA
关键字:DNA/intercalation/ dioxins/water treatment. DNA can be readily purified from salmon milts, which is generally discarded as an industrial waste. Due to its unique double-stranded structure, DNA can bind other molecules through various interactions, such as intercalation, gr...
http://www.polymer.cn/research/dis_info3118 |
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Synthesis of Novel Amphiphilic Fluorescent Comb-like Copolymer and Interaction with DNA
关键字:amphiphilic copolymer, DNA, fluorescence DNA delivery is a key technique in basic biological research and gene therapy. The ues of nonviral gene carriers has been expanding due to many drawbacks of viral vectors.
http://www.polymer.cn/research/dis_info3099 |
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Modeling single chain elasticity of single-stranded DNA: A comparison of three models
关键字:single chain elasticity The
dominant models of polymers, i.e. the freely jointed chain (FJC) model, the wormlike
chain (WLC) model and the freely rotating chain (FRC) model are modified by
integrating the inherent single-molecule elasticity obtained from quantum
mechanics (QM) ab-initio calculations. The QM modified models have been
utilized to generate fitting curves for single-stranded DNA obtained in organic
solvent. ...
http://www.polymer.cn/research/sy_info19131 |
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Double Stranded DNA Dissociates into Single Strands when Dragged into a Poor Solvent
关键字:DNA, single molecule
DNA displays a richness of biologically relevant
supramolecular structures, which depend on both sequence and ambient. The effect of dragging
dsDNA from water into poor solvent on the double-stranded structure is still
unclear because of condensation. Here
we employ single molecule techniques based on atomic force microscopy and molecular dynamics (MD) simulations to investigate the change in...
http://www.polymer.cn/research/sy_info19127 |
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Self-assembly of water-soluble conjugated polymers on solid surface for cellular imaging and DNA assay
Conjugated polymers (CPs) have proven to be attractive materials for various optoelectronic applications including light-emitting diodes, field-effect transistors, and photovoltaic devices due to their excellent photo- and electroluminescent properties.
http://www.polymer.cn/research/dis_info16729 |
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