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Magnetic-DNA vector constructed from PDMAEMA polycation and PEGylated brush-type polyanion with crosslinkable shell
Gene therapy has been known as a promising treatment for numerous hard curable diseases, and its safety and efficiency play the most challenging role.
http://www.polymer.cn/research/dis_info16694 |
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ATP诱导的DNA突环结构的打开及其对DNA链替换反应的调控
关键字:DNA突环结构,ATP适配体,分子开关,DNA链替换反应 DNA分子具有精确的碱基识别能力和序列可编程性,作为一种理想组装材料,近年来已被用于设计构建纳米尺度的分子器件,这些运转和调控通常是经一系列精确有序的DNA链替换反应来实现的。
http://www.polymer.cn/research/dis_info15411 |
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Dominant Process Which Influence Optical DNA Sequence Detection using Conjugated Polymers
关键字:DNA Sequence Detection A fluorescence method for detecting a target nucleic acid sequence, in a strategy employing acombination of a labeled peptide nucleic acid (PNA-C*) probes and conjugated polymer (CCP)/surfactant system, in a simple, rapid, and sensitiv...
http://www.polymer.cn/research/dis_info8922 |
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Novel quasi-interpenetrating network/gold nanoparticles composite matrices for DNA sequencing performances by capillary electrophoresis
Sieving matrices are very important because they determine migration behavior and resolution of DNA during separation and sequencing analysis of DNA by capillary Electrophoresis (CE).
http://www.polymer.cn/research/dis_info8808 |
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Amphiphilic fluorescent tryptophan-containing copolymer: synthesis, characterization and interaction with DNA
关键字:amphiphilic copolymer, DNA, fluorescence Much attention has been paid to amphiphilic copolymers containing chromophores because of their unique photophysical and photochmical behavior in aqueous solution. Yokoyama et al. reported the use of amphiphilic copolymer in gene delivery&n...
http://www.polymer.cn/research/dis_info3289 |
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DNA AS A FUNCTIONAL MATERIAL —REMOVAL OF DIOXIN DERIVATIVES BY SALMON MILT DNA
关键字:DNA/intercalation/ dioxins/water treatment. DNA can be readily purified from salmon milts, which is generally discarded as an industrial waste. Due to its unique double-stranded structure, DNA can bind other molecules through various interactions, such as intercalation, gr...
http://www.polymer.cn/research/dis_info3118 |
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Synthesis of Novel Amphiphilic Fluorescent Comb-like Copolymer and Interaction with DNA
关键字:amphiphilic copolymer, DNA, fluorescence DNA delivery is a key technique in basic biological research and gene therapy. The ues of nonviral gene carriers has been expanding due to many drawbacks of viral vectors.
http://www.polymer.cn/research/dis_info3099 |
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Fluorescent DNA Biosensor for Single-Base Mismatch Detection Assisted by Cationic Comb-Type Copolymer
Simple and rapid detection of DNA single base mismatch or point mutation is of great significance for the diagnosis, treatment, and detection of single nucleotide polymorphism (SNP) in genetic diseases. Homogeneous mutation assays with fast hybridization kinetics and amplified discrimination signals facilitate the automatic detection. Herein we report a quick and cost-effective assay for SNP ana...
http://www.polymer.cnt//ss/dujie/publicationsshow_13840.html |
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A Label-Free Fluorescent DNA Calculator Based on Gold Nanoparticles for Sensitive Detection of ATP
Herein we described a deoxyribonucleic acid (DNA) calculator for sensitive detection of
the determination of adenosine triphosphate (ATP) using gold nanoparticles (GNP) and PicoGreen fluorescence dye as signal transducer, and ATP and single-stranded DNA (DNA-M0) as activators. The calculator-related performances including linearity, reaction time, logic gate, and selectivity were investigated...
http://www.polymer.cnt//ss/dujie/publicationsshow_13838.html |
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Chaperone Copolymer-Assisted Aptamer-Patterned DNA Hydrogels for Triggering Spatiotemporal Release of Protein
In this paper, a DNA hydrogel with low DNA concentration, short sticky end, and good mechanical strength was simply prepared via one-pot self-assembly from two kinds of DNA
building block (X- and L-shaped DNA units) chaperoned by a cationic comb-type copolymer (CCC). The gelling process was completed under physiological conditions within 1 min, and the reversible sol?gel phase transition was ...
http://www.polymer.cnt//ss/dujie/publicationsshow_13835.html |
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