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J. Am. Chem. Soc. 2006: Weakly bound water molecules shorten single-stranded DNA
In this paper, we measure
the single chain elasticity of an oligomer ssDNA in both aqueous and
non-aqueous, apolar liquid environments by AFM-based single molecule force
spectroscopy. We find a marked deviation between the force-extension relations
recorded in the two ambients. This difference is attributed to the additional
energy required to break the H-bond directed water bridges around ssDNA c...
http://www.polymer.cnt//ss/cuishuxun/publicationsshow_8211.html |
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J. Am. Chem. Soc. 2007: Double Stranded DNA Dissociates into Single Strands when Dragged into a Poor Solvent
DNA displays a richness of biologically relevant
supramolecular structures, which depend on both sequence and ambient. The effect of dragging
dsDNA from water into poor solvent on the double-stranded structure is still
unclear because of condensation. Here
we employ single molecule techniques based on atomic force microscopy and molecular dynamics (MD) simulations to investigate the change in...
http://www.polymer.cnt//ss/cuishuxun/publicationsshow_8210.html |
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Studies on Synthesis of Water-Soluble Polymer-supported Transition Metal Polypyridyl Complexes and their interaction with DNA
Five water-soluble polymer-supported transition metal
polypyridyl complexes were synthesized from polyacrylic acid -co-
N-vinyl pyrrolidone, 2-methyl-3-hydroxyl benzaldehyde, o-phenanthroline and
metal acetate salts. Infrared spectra (IR), thermo-gravimetric and differential
thermal analysis (TG-DTA), Inductance Coupling Plasma (ICP) and X-ray
photoelectron spectroscopy (XPS) measurement technolog...
http://www.polymer.cnt//ss/zhangfaai/publicationsshow_7803.html |
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A label-free electrochemistry biosensor based flower-like 3-dimensional ZnO superstructures for detection of DNA arrays
A novel label-free DNA hybridization biosensor was fabricated using flower-like 3-dimensional (3D) ZnO superstructures as an enhanced sensing platform and employing chitosan (CS) as a film-forming material. A highly sensitive electrochemical DNA sensor was constructed by homogenously distributing Au nanoparticles (AuNPs) on the ZnO–CS matrix. The electrochemical performance of the designed elec...
http://www.polymer.cnt//ss/zhangqiuyu/publicationsshow_7790.html |
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Local gene delivery of PEI-PBLG/DNA complex from hydrogel and its potential application in tissue regeneration
3nd Symposium of Asia3 Foresight Program on Gene Delivery.Korea, 2007
http://www.polymer.cnt//ss/pbzhang/publicationsshow_7022.html |
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Mg2+/Ca2+ binding to DNA bases: a quantum chemical method and ABEEMrp/MM fluctuating charge model study
The interactions of Mg2+ and Ca2+ binding to adenine, cytosine, guanine, and thymine at various binding sites were studied by a high-level quantum chemical method and ABEEMrp/MM fluctuating charge model. The geometries and binding energies of M2+-bases complexes were determined at CCSD(T)/6-311++G(2d,2p)//MP2/6-311++G(2d,2p) level of theory, with the basis set&nb...
http://www.polymer.cnt//ss/cyyu/publicationsshow_6723.html |
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2-Methyl-3-chloro-9-hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidine Hydrochloride: Crystal Structure and Interaction with DNA
The title compound, C9H8ClN2O2+Cl-,is a hydrochloric acid salt of 2-methyl-3-chloro-9- hydroxy-4H-pyrido[1,2-a]pyrimidine-4-one, which is an important intermediate for the synthesis of biologically active heterocyclic compounds. The synthesized compound was characterized by 1H NMR and X-ray crystallography. The structure was solved in monoclinic, space group P21/n with a = 11.8295 (12), b = 6.2214...
http://www.polymer.cnt//ss/sunbw/publicationsshow_6103.html |
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Synthesis, crystal structure and DNA binding properties of a new member of the [Mn3Zn2](13+) complex family
Two new 1-D coordination polymers [MII(3-Bzpy)2(N(CN)2)2](M = Cd (1), Cu (2), 3-Bzpy =3-benzoylpyridine) have been synthesized and structurally characterized by single-crystal X-ray diffraction and IR. Single-crystal X-ray diffraction reveals that the complexes 1 and 2 are isostructural and all crystallize in mono-clinic P21/c space group with cell dimensions: a =6.3889(16) A。, b = 7.6496(12) A。...
http://www.polymer.cnt//ss/sunbw/publicationsshow_6100.html |
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Poly(2-aminoethyl methacrylate) with well-defined chain length for DNA vaccine delivery to dendritic cells
Poly(2-aminoethyl methacrylate) (PAEM) homopolymers with defined chain length and narrow molecular weight distribution were synthesized using atom transfer radical polymerization (ATRP), and a comprehensive study was conducted to evaluate the colloidal properties of PAEM/plasmid DNA polyplexes, the uptake and subcellular trafficking of polyplexes in antigen-presenting dend...
http://www.polymer.cnt//ss/tangrupei/publicationsshow_5497.html |
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Journal of Materials Chemistry 2011: Dendrimer modified magnetic iron oxide nanoparticle/DNA/PEI ternary magnetoplexes: a novel strategy for magnetofection
As a powerful technology to enhance the efficiency of gene delivery, magnetofection has attracted considerable attention in the past decade. In this work, we introduced 6 generation of PAMAM dendrimer modified superparamagnetic nanoparticles (DMSPION-G6) to PEI/DNA polyplexes by a two-step process and enhanced the transfection efficiency of PEI with the help of a magnetic field. We prepared DMSPIO...
http://www.polymer.cnt//ss/huangshiwen/publicationsshow_3464.html |
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