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Synthesis and properties of couplable ABCDE star copolymers by orthogonal CuAAC and Diels-Alder click reactions
The exploration on robust methods to construct star copolymers has attracted much attention. Owing to the great challenge in synthesis, the examples of miktoarm stars with chemical compositions up to five or more are very scarce. This study aims at developing a modular and orthogonal approach to synthesize multicomponent stars via a one-pot strategy using distinct building blocks. Tandem CuAAC and...
http://www.polymer.cnt//ss/zhaoyouliang/publicationsshow_10096.html |
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[Macromol. Biosci.] Acid-cleavable Unimolecular Micelles of Amphiphilic Star Copolymers for Potential Triggered Release of Anticancer Drugs
Shan Zhang, JianbinXu, Heng Chen*, Zhangfa Song, Yanla Wu, Xingyi Dai and Jie Kong*,
Acid-cleavable Unimolecular Micelles of Amphiphilic Star Copolymers for Potential Triggered Release of Anticancer Drugs, Macromolecular Bioscience, 2016, 2017, 17(3), 10.1002/mabi.201600258
链接：http://onlinelibrary.wiley.com/wol1/doi/10.1002/mabi.201600258/abstract
In this c...
http://www.polymer.cnt//ss/kongjie/publicationsshow_9569.html |
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Star-Shaped Amphiphilic Hyperbranched Polyglycerol Conjugated with Dendritic Poly(l-lysine) for the Codelivery of Docetaxel and MMP-9 siRNA in Cancer Therapy
The drug/gene co-delivery is a promising strategy for cancer treatment. Herein, to realize the co-delivery of docetaxel and MMP-9 siRNA plasmid efficiently into tumor cells, a star-shaped amphiphilic copolymer consisting of hyperbranched polyglycerol derivative (HPG-C18) and dendritic poly(L-lysine) (PLLD) was synthesized by the click reaction between azido-modified HPG-C18 a...
http://www.polymer.cnt//ss/madong/publicationsshow_9208.html |
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A star-shaped porphyrin-arginine functionalized poly(L-lysine) copolymer for photo-enhanced drug and gene co-delivery
The co-delivery of drug and gene has become the primary strategy in cancer and other disease therapy.
To co-deliver hydrophobic drug and functional gene efficiently into tumor cells, a star-shaped copolymer
(PP-PLLD-Arg) with a photochemical internalization effect consisting of a porphyrin (PP) core and
arginine-functionalized poly(L-lysine) dendron (PLLD-Arg) arms has been designed, an...
http://www.polymer.cnt//ss/madong/publicationsshow_9044.html |
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Tuning multiple arms for camptothecin and folate conjugations on star-shaped copolymers to enhance glutathione-mediated intracellular drug delivery.
Y. Zhang, M.H. Chen, X.M. Luo, H. Zhang, C.Y. Liu, H.Y. Li, X.H. Li*. Tuning multiple arms for camptothecin and folate conjugations on star-shaped copolymers to enhance glutathione-mediated intracellular drug delivery. Polym. Chem., 6, 2192 – 2203 (2015).
http://www.polymer.cnt//ss/xiaohongli/publicationsshow_8931.html |
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Amphiphilic star-block copolymers based on a hyperbranched core: Synthesis and supramolecular self-assembly
Novel amphiphilic star-block copolymers, star poly(caprolactone)-block-poly[(2-dimethylamino)ethyl methacrylate] and poly(caprolactone)-block-poly(methacrylic acid), with hyperbranched poly(2-hydroxyethyl methacrylate) (PHEMA–OH) as a core moiety were synthesized and characterized. The star-block copolymers were prepared by a combination of ring-opening polymerization and atom transfer radical po...
http://www.polymer.cnt//ss/zhouyongfeng/publicationsshow_8091.html |
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Synthesis of a Multi Alternating-Arm-Containing Dendritic Star Copolymer by RAFT and Cationic Ring-Opening Polymerization
A
new dendritic heteroarm star copolymer that contains multi-alternating
arms of poly(ethylene oxide-tetrahydrofuran) (P(EO-THF)) and poly(methyl
methacrylate) (PMMA) on a dendritic polyester core has been synthesized
by a ‘core-first’ approach by combination of sequential cationic
ring-opening polymerization (CROP) and reversible addition–fragmentation
transfer (RAFT) poly...
http://www.polymer.cnt//ss/zhouyongfeng/publicationsshow_8082.html |
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Synthesis and Supramolecular Self-Assembly of Thermosensitive Amphiphilic Star Copolymers Based on a Hyperbranched Polyether Core
A novel amphiphilic thermosensitive star copolymer with a hydrophobic
hyperbranched poly (3-ethyl-3-(hydroxymethyl)oxetane) (HBPO) core and
many hydrophilic poly(2-(dimethylamino) ethyl methacrylate) (PDMAEMA)
arms was synthesized and used as the precursor for the aqueous solution
self-assembly. All the copolymers directly aggregated into core–shell
unimolecular micelles (around 10 nm) and s...
http://www.polymer.cnt//ss/zhouyongfeng/publicationsshow_8079.html |
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Flocculation-Resistant Multimolecular Micelles with Thermo-Responsive Corona from Dendritic Heteroarm Star Copolymers
In this article, we report the self-assembly of flocculation-resistant
multimolecular micelles with thermoresponsive corona from novel
dendritic heteroarm star copolymers. The micelles have a
core-shell-corona structure at room temperature according to pyrene
probe fluorescence spectrometry, proton nuclear magnetic resonance (1H
NMR), transmission electron microscopy, and dynamic light ...
http://www.polymer.cnt//ss/zhouyongfeng/publicationsshow_8043.html |
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Layer-by-layer supramolecular assemblies based on linear and star-shaped poly(glycerol methacrylate)s for doxorubicin delivery.
poly(glycerol methacrylate)s for doxorubicin delivery
http://www.polymer.cnt//ss/gaohui/publicationsshow_7994.html |
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