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Hydrophilic nanoreservoirs embedded into polymeric nanoparticles - An approach to compatibilize polar molecules with hydrophobic matrices.
writer:2. H. Gao, M.-C. Jones, J. Chen, Y.R. Liang, R. E. Prud’homme, J.-C. Leroux,
keywords:Reverse micelles , hydrophilic guest molecules , polyester
source:期刊
specific source:Chem Mater, 2008; 20: 4191–4193.
Issue time:2008年

Reverse micelles formed hydrophilic nanodomains within hydrophobic polymeric particles. This technique is efficient, versatile, and simple. It allows the incorporation of hydrophilic guest molecules into biodegradable polymeric micro- or nanoparticles with high efficiencies making this approach particularly interesting for drug delivery applications, especially in the field of vaccination.