作者：Mei Shi, Xin-rui Duan, Zhao-tie Liu, Zhong-wen Liu and Jin-qiang Jiang**
关键字：Borate; Diethanol ammonium; Polybetaine; Thermal-sensitivity; UCST
论文来源：期刊
具体来源：Chinese Journal of Polymer Science Vol. 34, No. 6, (2016), 777?784
发表时间：2016年

A betaine-type styrene monomer with the quaternary ammonium-borate anion inner-salt pair was synthesized through the quaternization reaction and polymerized to afford the target polybetaine of poly(4-vinylbenzyl methyl-diethanol ammonium borate) (PVMAB). The chemical structures of the monomer and polymer were well demonstrated with 1H-NMR and 11B-NMR spectra analysis. The thermal-sensitive experiment showed that PVMAB in water afforded gradually welldefined sigmoidal transmittance-temperature (T-t) curves along with the increasing polymer concentration. However, the phase transition temperatures at the bottom of the S-shaped curves were always below 10 °C due to the very weak zwitterionic association of the ammonium-borate inner-salt pairs. The UCST phase transition could also be tuned by changing the ethanol content in the ethanol/water mixture. And the cytotoxicity experiment demonstrated the good biomimetic property of PVMAB. This study enriches the toolbox of polybetaines by introducing the quaternary ammoniumborate anion zwitterionic pair in the repeat units, therefore broadens the scope of synthetic polybetaines.