作者：Xiaobo Nie, Wei Jiang
关键字：三嵌段共聚物, 自组装, 多隔室胶束, 超分子聚合物, 氢键
论文来源：期刊
具体来源：Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2019, 581, 123839
发表时间：2019年

摘要：本文介绍了一种通过结合自组装和氢键作用调控ABC三嵌段共聚物在选择性介质中聚集体形貌的简便方法。以聚苯乙烯-b-聚1,4-丁二烯-b-聚2-乙烯基吡啶（PS-b-PBd-b-P2VP）作为ABC三嵌段共聚物，在甲苯和甲醇混合溶剂中自组装形成圆盘状胶束，其中PBd构成圆盘主体、部分PS域位于核内、其余PS作为凸起、P2VP作为冠层。向组装体系加入油酸（OA）后，OA与三嵌段共聚物的P2VP通过氢键形成超分子聚合物PS-b-PBd-b-P2VP(OA)，在氢键辅助下形成饼干状和蘑菇状胶束。有趣的是，通过改变甲苯和甲醇的体积比，饼干状和蘑菇状胶束可通过分裂和融合机制相互转变。因此，该研究为通过调控氢键和选择性溶剂含量控制嵌段共聚物聚集体形貌提供了一种简单方便的方法；ABC三嵌段共聚物形成的多隔室胶束在药物递送、靶向、催化等领域具有潜在应用。

Abstract：A facile method is introduced to tune the aggregate morphologies of ABC triblock copolymer in selective media by combining the self-assembly and hydrogen bonding. Poly(styrene)-block-poly(1,4-butadiene)-block-poly(2-vinyl pyridine), abbreviated for PS-b-PBd-b-P2VP and used as an ABC triblock copolymer, self-assembles in toluene and methanol mixture to form discoid micelles with PBd as the disk containing part of PS domains in the core, other PS as bumps and P2VP as corona, respectively. When oleic acid (OA) is added in the assembly system, supramolecular polymer PS-b-PBd-b-P2VP(OA) is prepared by the hydrogen bonding between OA and P2VP of triblock copolymer. As a result, biscuit-like and mushroom-like micelles are formed with assistance of hydrogen bonding. Interestingly, the biscuit-like and mushroom-like micelles can transform reciprocally by fission and fusion mechanism through varying the volume ratio of toluene and methanol. Thus, it provides a simple and convenient approach to control the aggregate morphologies of block copolymers by tuning the hydrogen bonding and selective solvent content. The multicompartment micelles from ABC triblock copolymer may present potential applications in drug delivery, targeting, catalysis and others.

论文链接：https://doi.org/10.1016/j.colsurfa.2019.123839