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In Vivo MRI and X-Ray Bifunctional Imaging of Polymeric Composite Supplemented with GdPO4·H2O Nanobundles for Tracing Bone Implant and Bone Regeneration
writer:Jing Huang, Zhongwen Lv, Yu Wang,Zongliang Wang, Tianlin Gao, Ning Zhang, Min Guo,Haifeng Zou*,Peibiao Zhang*
keywords:Gadolinium phosphate, hydroxyapatite, Poly (lactic-co-glycolic acid), bone repair, radiography, MR imaging
source:期刊
specific source:Advanced Healthcare Materials, 2016, DOI: 10.1002/adhm.201600249
Issue time:2016年

Homogeneous and monodisperse GdPO4·H2O nanobundles are successfully synthesized via a solvothermal method. Then, GdPO4·H2O are incorporated into the composite of hydroxyapatite and poly(lactic-co-glycolic acid) to obtain a biodegradable and traceable bone implant. After implanted, the GdPO4·H2O/HA/PLGA implant and the newly formed bone can be easily traced and observed through the combination of magnetic resonance imaging and X-ray imaging.


 全文详见: http://onlinelibrary.wiley.com/doi/10.1002/adhm.201600249/full