相关链接
联系方式
  • 通信地址:南京仙林大学城南师大化科院
  • 邮编:210023
  • 电话:N
  • 传真:
  • Email:bioalchem@yahoo.com
当前位置:> 首页 > 论文著作 > 正文
53. Extraction, characterization, and NO release potential of keratin from human hair
作者:Xingxing Jin, Yanfang Wang, Jiang Yuan, Jian Shen
关键字:Keratin
论文来源:期刊
具体来源:Materials Letters 175 (2016) 188–190
发表时间:2016年

Keratin-based biomaterials have emerged as potential candidates for various biomedical and biotechnological applications due to their intrinsic biocompatibility, biodegradability, mechanical durability, and natural abundance. The objective of our study is to explore the feasibility and potential applications of keratin for promoting nitric oxide (NO) release. Herein, keratin was ?rst extracted from human hair and then modi?ed with iodoacetic acid to afford S-carboxymethyl keratin. The amino acid residues, isoelectric point, and molecular weight of keratin were quanti?ed with amino acid analyzer, zeta potential measurement, and SDS-PAGE method. Interestingly, human hair keratin was proved to be capable of promoting NO release from endogenous donor of S-nitrosoglutathione (GSNO) in the presence of glutathione.