作者：Mingchen Yang, Chengling Huang, Hou-Yong Yu, Yanjuan Dong, Somia Yassin Hussain Abdalkarim
关键字：Rapid polymerization, Bilayer composites,Wound dressing
论文来源：期刊
发表时间：2023年

Hydrogels with excellent high-water uptake and flexibility have great potential for wound

dressing. However, pure hydrogels without fiber skeleton faced poor water retention, weak

fatigue resistance, and mechanical strength to hinder the development of the dressing as nextgeneration functional dressings. We prepared an ultrafast gelation (6s) Fe³⁺/TA-CNC

hydrogel (CTFG hydrogel) based on a self-catalytic system and bilayer self-assembled

composites. The CTFG hydrogel has excellent flexibility (800% of strain), fatigue resistance

(support 60% compression cycles), antibacterial, and self-adhesive properties (no residue or

allergy after peeling off the skin). CTFG@S bilayer composites were formed after

electrospun silk fibroin (SF) membranes were prepared and adhesive with CTFG hydrogels.

The CTFG@S bilayer composites had significant UV-shielding (99.95%), tensile strain

(210.9 KPa), and sensitive humidity-sensing properties. Moreover, the integrated structure

improved the mechanical properties of electrospun SF membranes. This study would provide

a promising strategy for rapidly preparing multifunctional hydrogels for wound dressing.