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Phosphorus-doped graphene-based electrochemical sensor for sensitive detection of acetaminophen
作者:Xuan Zhang*; Kai-Ping Wang; Li-Na Zhang; Yi-Chi Zhang; Li Shen
关键字:electrochemical sensor
论文来源:期刊
具体来源:Analytica Chimica Acta, 2018, 1036, 26-32.
发表时间:2018年
Phosphorus-doped graphene (P-RGO) was synthesized and employed as active electrode material to construct electrochemical sensor for acetaminophen (AP). The P-RGO coated glass carbon electrode (P-RGO/GCE) showed an excellent electrocatalytic activity for the oxidation of AP, resulted from highly enhanced electrochemical conductivity and accelerated electron transfer. The experimental conditions for AP detection were optimized, and under the optimal condition, a linear relationship between current intensity and concentration of AP was obtained in the range of 1.5–120?μM with a detection limit of 0.36?μM?(S/N?=?3). The developed sensor showed high selectivity for AP in the presence of various common species, excellent reproducibility and stability. The present sensor was also successfully applied for AP detection in pharmaceutical tablet samples.