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POLYMERIC MICELLES WITH TUNABLE CHANNELS FOR CONTROLLED RELEASE AND ORAL DELIVERY
关键字：polymeric micelles, tunable channels, controlled release, oral delivery
Two kinds of polymeric micelles with tunable channels (PMTC) have been prepared with diblock copolymers and used for ibuprofen controlled-release and oral insulin delivery, respectively. PMTC could effectively control the release rate of&nb...
http://www.polymer.cn/research/dis_info13846 |
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POLYMERIC MICELLES WITH TUNABLE CHANNELS FOR CONTROLLED RELEASE AND ORAL DELIVERY
关键字：polymeric micelles, tunable channels, controlled release, oral delivery
Two kinds of polymeric micelles with tunable channels (PMTC) have been prepared with diblock copolymers and used for ibuprofen controlled-release and oral insulin delivery, respectively. PMTC could effectively control the release rate of&nb...
http://www.polymer.cn/research/dis_info13846 |
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Carbohydrate Polymers 2012. 87, 790
关键字：sodium-alginate bead, micelle, drug release, composite, oral delivery
Micelles/sodium-alginate composite gel beads (micelles/SA beads) were constructed from SA matrix and indomethacin (IND) loaded six-arm block copolymer poly(ε-caprolactone)-block-(dimethylamino)ethyl methacrylate (S(PCL-b-PDMA)6) micelles. The morphology, swelling property and drug loading level of the beads were investigated. The release behaviors of three matrices including micelles, SA b...
http://www.polymer.cn/research/sy_info14681 |
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Food Rheology during Oral Processing Using a Model System
Gels from gellan gum and a mixture of gellan and psyllium seed gums were subjected to instrumental “mastication” using a simulator in the presence and absence of artificial saliva. Model bolus from the binary gel showed&nbs...
http://www.polymer.cn/research/dis_info12864 |
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Carbohydrate Polymers 2012. 87, 790
关键字：sodium-alginate bead, micelle, drug release, composite, oral delivery
Micelles/sodium-alginate composite gel beads (micelles/SA beads) were constructed from SA matrix and indomethacin (IND) loaded six-arm block copolymer poly(ε-caprolactone)-block-(dimethylamino)ethyl methacrylate (S(PCL-b-PDMA)6) micelles. The morphology, swelling property and drug loading level of the beads were investigated. The release behaviors of three matrices including micelles, SA b...
http://www.polymer.cn/research/sy_info14681 |
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Food Rheology during Oral Processing Using a Model System
Gels from gellan gum and a mixture of gellan and psyllium seed gums were subjected to instrumental “mastication” using a simulator in the presence and absence of artificial saliva. Model bolus from the binary gel showed&nbs...
http://www.polymer.cn/research/dis_info12864 |
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Recent advances in liposome surface modification for oral drug delivery
Oral delivery via the gastrointestinal (GI) tract is the dominant route for drug administration. Orally delivered liposomal carriers can enhance drug solubility and protect the encapsulated theraputic agents from the extreme conditions found in the GI tract. Liposomes, with their fluid lipid bilayer membrane and their nanoscale size, can significantly improve oral absorption. Unfortunately, the ...
http://www.polymer.cn//ss/yangguang/publicationsshow_9581.html |
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100. A composite hydrogel system containing glucose-responsive nanocarriers for oral delivery of insulin
Development of an oral delivery strategy for insulin therapeutics has drawn much attention in recent years. In this study, a glucose-responsive nanocarriers for loading of insulin has been prepared firstly. The resultant nanocarriers exhibited relative low cytotoxicity against Caco-2 cells and excellent stability against protein solution. The insulin release behaviors we...
http://www.polymer.cn//ss/ghjiang_cn/publicationsshow_9219.html |
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Chitosan-coated nano-liposomes for the oral delivery of berberine hydrochloride
Abstract: Berberine hydrochloride (BH) possesses various pharmacological properties including anticancer; unfortunately, it has low oral bioavailability and potential side effects for its parenteral administration. Nanoscale delivery carriers can increase the oral bioavailability of BH. Chitosan has interesting biopharmaceutical properties such as nontoxicity, biocompatibility, biodegradability, a...
http://www.polymer.cn//ss/yangguang/publicationsshow_7733.html |
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Oral glucose- and pH-sensitive nanocarriers for simulating insulin release in vivo.
drug delivery
http://www.polymer.cn//ss/zhangxinge/publicationsshow_7629.html |
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