作者：Huiqi Zhang*
关键字：Water-Compatible, Fluorescent, Molecularly Imprinted Polymers
论文来源：其他
具体来源：Methods in molecular biology (Clifton, N.J.) 2021, 2359, pp97-108.
发表时间：2021年
Preparation of molecularly imprinted polymers (MIPs) capable of directly and selectively recognizing small organic analytes in aqueous samples (particularly in the undiluted complex biological samples) is described. Such water-compatible MIPs can be readily obtained by the controlled grafting of appropriate hydrophilic polymer brushes onto the MIP particle surfaces. Two types of synthetic approaches (i.e., "two-step approach" and "one-step approach") for preparing complex biological sample-compatible hydrophilic fluorescent MIP nanoparticles and their applications for direct, selective, sensitive, and accurate optosensing of an antibiotic (i.e., tetracycline (Tc)) in the undiluted pure bovine/porcine serums are presented.