writer：张黎明等 // Zhang, L. M.; et al
keywords：天然大分子，生物大分子, 功能材料, 杂化材料 // Natural macromolecules, Biomacromolecules, Functional materials, Hybrid materials
source：期刊
Issue time：2026年

*Corresponding author(s)/通讯作者. #These authors contributed equally to this work/共同第一作者.   

[384] Yang, H. K.; Zhang, L. M. * Preparation, self-assembly, loading drug, blood clotting and hemolysis of amphiphilic diblock copolymers based on α-alkyne poly(ε-benzyloxycarbonyl-L-lysine) and α-azido heparin. Colloids and Surfaces A-Physicochemical and Engineering Aspects, 2026, incomplete submission.

[383] Deng, J. J.#; Chen, S. S.#.; Li, N.#; Zhou, J. Y.; Lao, G. J.; Ren, M.; Yang, C.; Yan, L.*; Zhang, L. M.*Amphiphilic beta-cyclodextrin-centered heteroarm star polymers toward the co-delivery of methotrexate and plasmid DNA. Journal of Biomaterials Science, Polymer Edition, 2026, incomplete submission.

[382] Zhang, J. Z. #; Liang, H. S. #; Mao, X. H.; Wang, F.*; Huang, L. L.*; Zhang, L. M.* Gene delivery therapy and photothermal therapy of osteosarcoma via multifunctional spermine-modified amylose@IR-780 nanocomplexes. Biomacromolecules, 2026, incomplete submission.

[381] Wang, H. Z.; Lu, B.; Guo, S.-Z.*; Zhang, L. M.* From Jenga-style to Wound Repair: Structural and Therapeutic Potential of a Gas-Releasing, pH/Glucose-Responsive Biomass Hydrogel. Advanced Functional Materials, 2026, Confirming your submission.

[380] Lu, B.; Zhou, J. Y.; Wang, H. Z.; Lai, J. Y.; Zheng, X.; Guo, S.-Z.*; Zhang, L. M.* Intelligent ROS-Triggered NO and Isotretinoin Co-Delivery Hydrogel Dressings for Microenvironment Modulation and Rapid Repair of Diabetic Wounds. Chemical Engineering Journal, 2026, Confirming your submission. 

[379] Zheng, X.; Zhou, J. Y.; Wang, H. Z.; Lu, B.; Lai, J. Y.; Guo, S.-Z.*; Zhang, L. M.* Dual-Modality Cancer Therapy via Light-Triggered CO Release and Photothermal Effects from Engineered Prussian Blue Nanoparticles. Small,  2026, Confirming your submission.

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[学术会议/Scientific Conferences-160] 陆滨，王含章，郭双壮*，张黎明*. 新型智能水凝胶用于糖尿病伤口 (墙报).  中国化学会第35届学术年会, 2026年4月11日至14日在重庆市举行，4月10日报到。 https://www.chemsoc.org.cn/meeting/35th/

摘要：糖尿病慢性创面因长期炎症反应、细菌感染以及组织再生能力受损而难以愈合，仍是亟待解决的临床问题。本研究构建了一种活性氧响应型一氧化氮释放水凝胶体系，以三羟甲基氨基甲烷改性的透明质酸为基体，引入具有天然抗菌活性的 ε-聚赖氨酸，并结合功能化中空介孔杂化二氧化硅纳米颗粒，实现药物负载与刺激响应释放。该水凝胶可在温和条件下快速凝胶化，形成稳定三维网络结构，表现出良好的组织黏附性能、抗菌活性及促愈合潜能。通过结构与功能模块的理性设计，材料在氧化应激条件下可实现异维A酸的可控释放，并进一步触发按需 NO 生成。体内外实验表明，异维A酸与 NO 的释放均呈 ROS 水平依赖性且具可调控特征，从而显著促进创面闭合，增强胶原沉积与血管新生，并改善局部炎症微环境。该水凝胶体系具有良好的生物相容性与智能响应特性，提示其作为多功能创面敷料在糖尿病慢性创面高效治疗中具有潜在应用价值。