In this study, a series of comb-likemethoxy polyethylene glycol (MPEG)functionalized polyurethanes (PUs) (PU–g–MPEG)were successfullyprepared via ‘click’ chemistry and polyaddition reaction. The copper catalyzed Huisgen 1,3-dipolar cycloaddition was firstly
carried out between 3,5-bis(hydroxymethyl)-1-propargyloxybenzene (PBM) and methoxy polyethylene glycol azide (MPEG–N3) toobtain MPEGylated diol PBM (MPEG–PBM). Then, the comb-like PUs having MPEG located on the backbones (PU–g–MPEG)were synthesized through the polyaddition of MPEGylated diol PBM and hexamethylene diisocyanate (HDI). Fourier transforminfrared (FTIR), 1H NMR spectroscopy, size exclusion chromatography (SEC), and thermo gravimetric analyses (TGA) were used
to characterize these synthesized MPEG-functionalized comb-like PUs (PU–g–MPEG). Compared with PU without MPEG grafts,PU–g–MPEG show a better wettability.