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Bioavailability and preliminary toxicity evaluations of alumina nanoparticles in vivo after oral exposure
Bioavailability and preliminary toxicity evaluations of alumina nanoparticles in vivo after oral exposure
http://www.polymer.cnt//ss/yang/publicationsshow_7299.html |
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10. Disulfide cross-linked biodegradable polyelectrolyte nanoparticles as oral protein drugs delivery.
Polyelectrolyte nanoparticles were prepared by mixing chitosan (CS) and polyaspartic acid functionalized with cysteamine (PASP–CA) under mild conditions. The nanoparticles (NPs) included thiol moieties that were cross-linked to render the NPs stable at physiological pH. It was demonstrated that reacting the thiol moieties to form disulfide bonds led to improved stability. NPs without disulfi...
http://www.polymer.cnt//ss/zhangxinge/publicationsshow_4633.html |
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Polymeric Micelles with Tunable Channels for Controlled Drug Release
关键字：polymeric micelles, tunable channels, controlled release, oral delivery
Polymeric micelles with tunable channels (PMTC) have been prepared with two kinds of diblock copolymers and used for ibuprofen controlled-release and protective effects of polypeptide, respectively. PMTC could effectively control the ...
http://www.polymer.cn/research/dis_info16022 |
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Polymeric Micelles with Tunable Channels for Controlled Drug Release
关键字：polymeric micelles, tunable channels, controlled release, oral delivery
Polymeric micelles with tunable channels (PMTC) have been prepared with two kinds of diblock copolymers and used for ibuprofen controlled-release and protective effects of polypeptide, respectively. PMTC could effectively control the ...
http://www.polymer.cn/research/dis_info16022 |
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112. Preparation of poly(lactic-co-glycolic acid) and chitosan composite nanocarriers via electrostatic self assembly for oral delivery of insulin
To improve insulin bioavailability and overcome multiple barriers for oral delivery of insulin, the composite nanocarriers (PLGA/FA-CS) prepared from poly(lactide-co-glycoside) (PLGA) and folic acid modified chitosan (FA-CS) were fabricated via electrostatic self-assembly method. The resultant composite nanocarriers exhibited low cytotoxicity against HT-29 cells and excellent stability against p...
http://www.polymer.cnt//ss/ghjiang_cn/publicationsshow_10340.html |
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105. Oral delivery of insulin using CaCO3-based composite nanocarriers with hyaluronic acid coatings
Abstract: A facile and green reversed-phase microemulsion co-precipitation method has been developed for fabrication of CaCO3-based composite nanocarriers (NCs) with hyaluronic acid (HA) coatings for oral delivery of insulin. The cell viability of resultant CaCO3-based composite NCs against HT-29 cells was analyzed with different concentration. The chemical stability of loaded insulin against di...
http://www.polymer.cnt//ss/ghjiang_cn/publicationsshow_9755.html |
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102. Preparation of chitosan-based multifunctional nanocarriers overcoming multiple barriers for oral delivery of insulin
To overcome multiple barriers for oral delivery of insulin, the chitosan-based multifunctional nanocarriers modified by L-valine (LV, used as a target ligand to facilitate the absorption of the small intestine) and phenylboronic acid (PBA, used as a glucose-responsive unit) have been designed and evaluated in this study. The resultant nanocarriers exhibited low cytotoxicity against HT-29 cells a...
http://www.polymer.cnt//ss/ghjiang_cn/publicationsshow_9461.html |
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Vesicles Formed from Poly(lactic acid)-b-Pluronic-b-Poly(lactic acid) Block Copolymer as New Carriers for Oral Insulin Delivery
关键字：Vesicles,Formed,Poly,lactic,acid,Pluronic,Poly,lactic,acid,Block,Copolymer,New,Carriers,Oral,Insulin,Delivery,
Biocompatible amphiphilic block copolymers, poly(lactic acid)-b-Pluronic-b-poly(lactic acid) (PLA-F127-PLA), have been synthesized by our group.
http://www.polymer.cn/research/dis_info5864 |
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Vesicles Formed from Poly(lactic acid)-b-Pluronic-b-Poly(lactic acid) Block Copolymer as New Carriers for Oral Insulin Delivery
关键字：Vesicles,Formed,Poly,lactic,acid,Pluronic,Poly,lactic,acid,Block,Copolymer,New,Carriers,Oral,Insulin,Delivery,
Biocompatible amphiphilic block copolymers, poly(lactic acid)-b-Pluronic-b-poly(lactic acid) (PLA-F127-PLA), have been synthesized by our group.
http://www.polymer.cn/research/dis_info5864 |
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