Approach to Clinical Tissue Engineering，2005年新型纤维与聚合物材料国际学术会议（10.19-10.21，上海）-中国聚合物网,论文下载

Approach to Clinical Tissue Engineering

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Clinical Tissue Engineering

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分子表征

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2005年新型纤维与聚合物材料国际学术会议（10.19-10.21，上海）

简介：

Polymersandfibershavebeenusedintissueengineeringfortherestorationofseverelydiseasedorlosttissuesalongwithcells.Themajorfunctionofpolymersinthetissueengineeringissupportofcellsfortheirdifferentiation,proliferation,andextracellularmatrixformation.Toachievethisfunction,polymersareprocessedtotheshapeofscaffoldsandcarrierssoastoincorporatecellsandgrowthfactorsinsidethebiomaterials.Toallowforseedingcellsasmanyaspossibleandsufficientdeliveryofnutrientstotheincorporatedcells,scaffoldsshouldberesorbableandporouswithinterconnectedporosity.Fibersareveryusefulasastartingmaterialtofabricateporousscaffolds.Bioabsorbablefibersmadefrompolyglycolide(PGA)andpoly(glycolide-co-lactide)(PGLA)havebeenextensivelyappliedforscaffoldfabricationasnon-wovenfabrics.Poly(lactide-co-ε-caprolactone)[P(LA/CL)]alsohasahighpotentialasabiomaterialforscaffolds.WhentheLA/CLratioisaround50/50,thecopolymerexhibitselasticitywithlowYoung’smodulus.Thispresentationwilldisplaysomeclinicalapplicationsoftheseresorbablepolymersandfibersintissueengineeringofsofttissues.

作者：

Yoshito Ikada

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2007-08-06 13:29:01

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