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Differential Drug Delivery with Bacterial-Responsive Polymeric Nanoparticles  
Differential Drug Delivery with Bacterial-Responsive Polymeric Nanoparticles
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Nanoparticles that are responsive to the unique microenvironment of lesion sites have attracted widespread attention in drug delivery. Herein, we report a new strategy for differential drug delivery to bacterial infection sites through the development of bacterial-responsive polymeric nanoparticles. With a convenient “arm first” procedure via one-step ring-opening polymerization, we developed a lipase-sensitive polymeric triple-layered and polyphosphoester core-crosslinked nanogel.
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上传时间: 2013-12-19 14:37:20
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